General Secretary Xi Jinping’s thoughts on Party building contain a scientific way of thinking and working methods. From the perspective of thinking methods, the focus is on establishing and using strategic thinking, historical thinking, dialectical thinking, systematic thinking, innovative thinking, rule of law thinking, and bottom-line thinking to plan and promote party building in the new era. This fusion of established methods of thought seizes the law of party building from the complicated ruling environment while also enhancing the systematicity, synergy, creativity, and effectiveness of party building. From the perspective of working methods, this mode of thought has the flexibility to use a series of working methods that match today’s practice of party management and party governance. This includes adhering to problem-oriented and targeted therapy, paying attention to top-level design and overall planning, holding the “bull’s nose” and key breakthroughs, grasping the “key minority” and the above rate, advocating hard work and nailing nails, which effectively and efficiently solves the problem of party management and party governance in the new era. These scientific methods adhere to the Marxist world outlook and methodology. They carry the historical experience of party building in the new era, embody Xi Jinping’s methodological wisdom in the great practice of scientifically answering the question of “managing the party and governing the party,” and highlight the great and far-reaching theoretical, practical, and epochal significance.